God Hand are a powerful group of five reality warping angels (or demons), each corresponding to a finger or thumb, directly below the Idea of Evil in power and authority. All of them were originally humans who were chosen by the Idea of Evil to serve its purpose of giving reason for humanity's suffering. They each possessed and used a Crimson Behelit like the one Griffith used (The Egg of the Emperor) in order to transcend their humanity. It is unknown whether there are five Crimson Behelits or whether the same one came to each of them in turn.
The God Hand can't take corporeal form in the mortal plane. If they do appear there, it is a construct, formed by whatever is at hand. They can also appear when summoned by a Behelit for the purpose of creating Apostles or during the Eclipse which happens only once every 216 years and marks the birth of a new God Hand, wherein there is an area that acts as a junction in between the astral realm and the human realm. After the World Transformation can now manifest in the physical plane.
Most of the God Hand's names are inspired by Science-Fiction novels. It is also worth noting that the design of the God Hand characters show similarity to Cenobites from Hellraiser movie series, based on Clive Barker novella, of which Miura is believed to be a fan.
Despite their power, the God Hand cannot completely predict the flow of fate and causality nor are they invincible. Slan herself has admitted "[they] are not god himself".